The 13th EMSLIBS follows the tradition of precedent events, providing a diverse and exciting scientific program divided in thematic sessions, headed by a key note addressing, and including several invited speakers on topics such as: Fundamentals, Processing and Chemometrics, Instrumentation, novel approach and multimodal, Cultural heritage, Industry and Energy, Biology, Health and Agronomy, Environmental and geological sciences, Extreme Environments and nuclear applications. The program spans over 4 and a half days, and including some social events, in a relaxing environment, to discuss science surrounded by culture, tradition and gastronomy.